Selected Publications

1.   Tang M, Chen B, Xia H, Pan M, Zhao R, Zhou J, Yin Q, Wan F, Yan Y, Fu C, Zhong L, Zhang Q, Wang YG*. pH-gated nanoparticles selectively regulate lysosomal function of tumour-associated macrophages for cancer immunotherapy. Nature Communications. 2023, 14, 5888. 

2.   Chen B, Yan Y, Yang Y, Cao G, Wang X, Wang YQ, Wan F, Yin Q, Wang Z, Li Y, Wang L, Xu B, You F*, Zhang Q*, Wang YG*. A pyroptosis nanotuner for cancer therapy. Nature Nanotechnology. 2022, 17, 788-798. 

3.   Yan Y, Chen B, Yin Q, Wang Z, Yang Y, Wan F, Wang YQ, Tang M, Wang S, Zhang Q, Wang YG*. Dissecting extracellular and intracellular distribution of nanoparticles and their Contribution to therapeutic response by monochromatic ratiometric imaging. Nature Communications. 2022, 13, 2004. 

4.    Zhao R, Fu C, Wang Z, Pan M, Ma B, Yin Q, Chen B, Liu J, Xia H, Wan F, Wang L, Zhang Q, Wang YG*. A pH-responsive nanoparticle library with precise pH tunability by co-polymerization with non-ionizable monomers. Angewandte Chemie International Edition. 2022, 61, e202200152. (VIP paper)

5.   Xia H, Qin M, Wang Z, Wang YQ, Chen B, Wan F, Tang M, Pan X, Yang Y, Liu J, Zhao R, Zhang Q, Wang YG*. A pH-/enzyme-responsive nanoparticle selectively targets endosomal toll-like receptors to potentiate robust cancer vaccination. Nano Letters. 2022, 22, 2978-2987. 

6.     Yin Q, Pan A, Chen B, Wang Z, Tang M, Yan Y, Wang YQ, Xia H, Chen W, Du H, Chen M, Fu C, Wang YN, Yuan X, Lu Z, Zhang Q, Wang YG*. Quantitative imaging of intracellular nanoparticle exposure enables prediction of nanotherapeutic efficacy. Nature Communications. 2021, 12, 2385. 

7.     Zhang J, Rakhimbekova A, Duan X, Yin Q, Foss CA, Fan Y, Xu Y, Li X, Cai X, Kutil Z, Wang P, Yang Z, Zhang N, Pomper MG, Wang YG*, Bařinka C*, Yang X*. A prostate-specific membrane antigen activated molecular rotor for real-time fluorescence imaging. Nature Communications. 2021, 12, 5460. 

8.   Wang Z, Xia H, Chen B, Wang YQ, Yin Q, Yan Y, Zhang Q, Wang YG*. pH-amplified CRET nanoparticles for in vivo imaging of tumor metastatic lymph nodes. Angewandte Chemie International Edition. 2021, 133, 14633-14641. (Hot paper)

9.    Du H, Zhao S, Wang YQ, Wang Z, Chen B, Yan Y, Yin Q, Liu D, Wan F, Zhang Q, Wang YG*. pH/cathepsin B hierarchical responsive nano-conjugates for enhanced tumor penetration and chemo-immunotherapy. Advanced Functional Materials. 2020, 30, 2003757. 

10.  Wang YG, Zhou KJ, Huang G, Hensley C, Huang XN, Ma XP, Zhao T, Sumer BD, DeBerardinis RJ, Gao JM*. A nanoparticle-based strategy for the imaging of a broad range of tumours by nonlinear amplification of microenvironment signals. Nature Materials. 2014, 13, 204-212. 

Education

• 2005.9-2008.7 Ph.D., Department of Pharmaceutics, Peking University, Beijing, China  (Advisor: Prof. Qiang Zhang)
• 2002.9-2005.7 M.Sc., Department of Pharmaceutics, Shenyang Pharmaceutical University, Shenyang, Liaoning, China (Advisor: Prof. Siling Wang)
• 1998.9-2002.7 B.Sc., School of Pharmacy, Shandong University, Jinan, Shandong, China

Award and Honors

• 2023     Tu Youyou Young Investigator Award
• 2022     Bayer Investigator Award
• 2022     National Natural Science Fund for Distinguished Young Scholars, NSFC
• 2019     Beijing Natural Science Fund for Distinguished Young Scholars, BJNSF
• 2017     Senofi Young Scientist Award in Bio-pharmaceuticals from Chinese Pharmaceutical Association
• 2016     National Natural Science Fund for Excellent Young Scholars, NSFC
• 2015     Young Scientist Award in Pharmaceutical Science from Chinese Pharmaceutical Association
• 2014     The Recruitment Program of Youth Experts, Peking University

Professional Career

• 2023.1-Present       Boya Distinguished Professor, School of Pharmaceutical Sciences, Peking University 
• 2021.8-2022.12      Associate Professor (with Tenure), School of Pharmaceutical Sciences, Peking University
• 2015.3-2021.7        Assistant Professor (Tenure Track), School of Pharmaceutical Sciences, Peking University
• 2010.6-2015.2        Postdoctoral Fellow, University of Texas Southwestern Medical Center (Advisor: Prof. Jinming Gao)
• 2008.7-2010.5        Postdoctoral Fellow, Institute of biophysics, Chinese Academy of Sciences (Advisor: Prof. Wei Liang)

Education

• 2005.9-2008.7         Ph.D. in Pharmaceutics, Peking University, Beijing, China (Advisor: Prof. Qiang Zhang)
• 2002.9-2005.7         M.Sc. in Pharmaceutics, Shenyang Pharmaceutical University, Shenyang, China (Advisor: Prof.  Siling Wang)
• 1998.9-2002.7         B.Sc. in Pharmacy, Shandong University, Jinan, China