Education and Professional Career
- 2025.8-present Associate Professor (research-track), School of Pharmaceutical Sciences, Peking University
- 2023.11-2025.8 Postdoctoral Fellow, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology
(Advisor: Prof. Daniel G. Anderson and Prof. Robert S. Langer)
- 2022.7-2023.7 Assistant Professor (research-track), School of Pharmaceutical Sciences, Peking University
- 2018.7-2022.6 Postdoctoral Fellow, School of Pharmaceutical Sciences, Peking University (Advisor: Prof. Yiguang Wang)
- 2015.9-2018.6 Ph.D. in Pharmaceutics, Peking University, Beijing, China (Advisor: Prof. Qiang Zhang and Prof. Yiguang Wang)
- 2013.9-2015.7 M.Sc. in Pharmaceutics, Peking University, Beijing, China (Advisor: Prof. Qiang Zhang)
- 2009.9-2013.7 B.Sc. in Pharmacy, Peking University, Beijing, China
Award and Honors
- 2025 National Natural Science Fund for Excellent Young Scholars, NSFC
- 2025 Beijing Nova Program of Science and Technology, BSTC
- 2024 Young Talent Promotion Project of Beijing Association for Science and Technology
- 2021 Outstanding Postdoctoral Prize of Peking University
- 2018 National Postdoctoral Program for Innovative Talents of China Postdoctoral Foundation
Selected Publications
1. Zhang Y†, Yan Y†, Liu J†, Xia H, Cui Y, Huang X, Chang J, Zhang W, Chen W, Zhang Q, Wang S*, Wang Y*, Chen B*. An Endoplasmic Reticulum Stress-Specific Nanoinducer Selectively Evokes Type-II Immunogenic Cell Death for Pyroptotic Cancer Immunotherapy. Advanced Materials. 2025, 10.1002/adma.202501953.
2. Lu X†, Xia H†, Gao W, Pan X, Yan Y, Zhang R, He Y, Wang YG, Chen BL*, Mei D*. A pH-responsive and guanidinium-rich nanoadjuvant efficiently delivers STING agonist for cancer immunotherapy. ACS Nano. 2025, 19, 6758-6770. (Highly cited paper)
3. Chen BL, Yan Y, Yang Y, Cao G, Wang X, Wang Y, Wan F, Yin Q, Wang Z, Li Y, Wang L, Xu B, You F*, Zhang Q*, Wang YG*. A pyroptosis nanotuner for cancer therapy. Nature Nanotechnology. 2022, 17, 788-798. (Highly cited paper)
4. Liu J#, Yan Y#, Zhang Y, Pan X, Xia H, Wan F, Huang X, Zhang Q, Chen BL*, Wang YG*. Lysosome-mitochondria cascade targeting nanoparticle drives robust pyroptosis for cancer immunotherapy. J. Am. Chem. Soc. 2024, 146, 34568-34582.
5. Wan F#, Wang L#, Zhao R, Xia H, Liu J, Yan Y, Deng F, Zhang Q, Wang YG*, Chen BL*. A general strategy towards early endosome-stressed nanophotosensitizers for pyroptotic cancer therapy. Nano Today. 2024, 57, 102350.
6. Qin M, Xia H, Xu W, Chen BL*, Wang YG*. The spatiotemporal journey of nanomedicines in solid tumors on their therapeutic efficacy. Advanced Drug Delivery Reviews. 2023, 203, 115137.
7. Yan Y†, Chen BL†, Yin Q, Wang Z, Yang Y, Wan F, Wang Y, Tang M, Xia H, Chen M, Liu J, Wang S, Zhang Q, WangYG*. Dissecting extracellular and intracellular distribution of nanoparticles and their contribution to therapeutic response by monochromatic ratiometric imaging. Nature Communications. 2022, 13, 2004.
8. Chen BL†, Yang Y†, Wang Y, Yan Y, Wang Z, Yin Q, Zhang Q, Wang YG*. Precise Monitoring of Singlet Oxygen in Specific Endocytic Organelles by Super-pH-Resolved Nanosensors. ACS Applied Materials &Interfaces. 2021, 13, 18533-18544.
9. Chen BL†, Dai W†*, Mei D, Liu T, Li S, He B, He B, Yuan L, Zhang H, Wang X, Zhang Q*. Comprehensively priming the tumor microenvironment by cancer-associated fibroblast-targeted liposomes for combined therapy with cancer cell-targeted chemotherapeutic drug delivery system. Journal of Controlled Release. 2016, 241, 68-80.
10. Chen BL, Dai W*, He B, Zhang H, Wang X, Wang YG, Zhang Q*. Current Multistage Drug Delivery Systems Based on the Tumor Microenvironment. Theranostics. 2017, 7, 538-558. (Highly cited paper)